Ar 11835

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Gene ID:	11835
Gene symbol:	ar
Gene Description:	androgen receptor
Aliases:	AW320017; Tfm
Human Ortholog Gene ID:	[367]
Reviewer Judgement:	TF Gene
Functional Classification:	DNA-Binding: sequence-specific

DBD Protein Group Classification:	Zinc-coordinating Group
DBD Protein Group/Family Classification:	Zinc-coordinating Group / Hormone-nuclear Receptor Family

Homolog Cluster(s):

110784

Evidence:

Pubmed ID	Function	Species	Evidence Strength	Reviewer's Comments	Reviewer
[7685765]	DNA Binding	Human	Strong	Gel-shift assay on the proximal promoter of the human glycoprotein hormone alpha subunit gene	Sarav Sundararajan
[9211894]	Transactivation; TF PPI	Human	Strong	luciferase reporter assays show that AR can induce the PSA proximal promoter, but that this induction is repressed by c-Jun. Co-immunoprecipitation experiments show that AR interacts with c-Jun and c-Fos	Sarav Sundararajan

Additional Reviewer Comments:

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Gene description	androgen receptor +
Gene id	11,835 +
Gene judgment	TF Gene +
Gene symbol	ar +, AW320017 +, and Tfm +
Gene taxonomy	DNA-Binding: sequence-specific +
Homolog cluster	110,784 +
Protein family	2.1 Zinc-coordinating Group/18 Hormone-nuclear Receptor Family +
Protein group	2.1 Zinc-coordinating Group +